Table 5. Consensus ACROBAT-NRSI judgments between two reviewers by domain of bias—component studies from McGettigan and Henry [18].

Component Study	Domain							Overall RoB Judgment
	Bias Due to Confounding	Bias in Selection of Participants	Bias in Measurement of Interventions	Bias Due to Departures from Intended Interventions	Bias Due to Missing Data	Bias in Measurement of Outcomes	Bias in Selection of Reported Results
Cohort study design
Curtis et al. [40]	Moderate	Moderate	Low	Moderate	Moderate	Low	Low	Serious
Gislason et al. [44]	Low	Low	Low	Low	Low	Low	Low	Low
MacDonald and Wei [51]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
Mamdani et al. [52]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
Ray et al. [54]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
Ray et al. [55]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
Case–control study design
Bak et al. [39]	Serious	Low	Low	Low	Low	Low	Low	Serious
Fischer et al. [41]	Moderate	Low	Low	Low	Moderate	Low	Low	Moderate
Garcia Rodriquez et al. [42]	Moderate	Low	Low	Low	Moderate	Low	Low	Moderate
Garcia Rodriquez et al. [43]	Moderate	Low	Low	Low	Moderate	Low	Low	Moderate
Graham et al. [45]	Low	Low	Low	Low	Low	Low	Low	Low
Hippisley-Cox and Coupland [46]	Moderate	Low	Low	Low	Moderate	Low	Low	Moderate
Johnsen et al. [40]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
Kimmel et al. [48]	Moderate	Moderate	Moderate	Low	Moderate	Low	Low	Serious
Kimmel et al. [49]	Moderate	Moderate	Moderate	Low	Moderate	Low	Low	Serious
Lévesque et al. [50]	Moderate	Low	Low	Low	Low	Low	Low	Moderate
McGettigan et al. [53]	Low	Low	Moderate	Low	Low	Low	Low	Moderate
Schlienger et al. [56]	Moderate	Low	Low	Low	Moderate	Low	Low	Moderate
Solomon et al. [57]	Moderate	Moderate	Low	Moderate	Low	Low	Moderate	Serious
Solomon et al. [58]	Low	Moderate	Low	Low	Low	Low	Low	Moderate
Watson et al. [59]	Low	Low	Low	Low	Moderate	Low	Low	Moderate