Table 1. Phase 2 (community based clinical setting) sensitivity, specificity, and predictive values for the 3 point-of-care tests to detect or exclude anemia.
Females (12 g/dl cut-off) | ||||||||
Point-of-care tests | reference | |||||||
Outcome | Positive | Negative | Subtotal | sensitivity | specificity | PPV | NPV | |
HemoCue | Positive | 26 | 8 | 34 | 72% | 70% | 76% | 66% |
Negative | 10 | 19 | 29 | |||||
Total | 36 | 27 | 63 | |||||
Stat-Site | Positive | 30 | 11 | 41 | 83% | 59% | 73% | 73% |
Negative | 6 | 16 | 22 | |||||
Total | 36 | 27 | 63 | |||||
URIT | Positive | 36 | 25 | 61 | 100% | 7% | 59% | 100% |
Negative | 0 | 2 | 2 | |||||
Total | 36 | 27 | 63 | |||||
Males (13 g/dl cut-off) | ||||||||
Point-of-care tests | reference | |||||||
Outcome | Positive | Negative | Subtotal | sensitivity | specificity | PPV | NPV | |
HemoCue | Positive | 2 | 10 | 12 | 50% | 70% | 17% | 92% |
Negative | 2 | 23 | 25 | |||||
Total | 4 | 33 | 37 | |||||
Stat-Site | Positive | 4 | 10 | 14 | 100% | 70% | 29% | 100% |
Negative | 0 | 23 | 23 | |||||
Total | 4 | 33 | 37 | |||||
URIT | Positive | 4 | 31 | 35 | 100% | 6% | 11% | 100% |
Negative | 0 | 2 | 2 | |||||
Total | 4 | 33 | 37 | |||||
Females and males (using the respective cut-off values) | ||||||||
Point-of-care tests | reference | |||||||
Outcome | Positive | Negative | Subtotal | sensitivity | specificity | PPV | NPV | |
HemoCue | Positive | 28 | 18 | 46 | 70% | 70% | 61% | 78% |
Negative | 12 | 42 | 54 | |||||
Total | 40 | 60 | 100 | |||||
Stat-Site | Positive | 34 | 21 | 55 | 85% | 65% | 62% | 87% |
Negative | 6 | 39 | 45 | |||||
Total | 40 | 60 | 100 | |||||
URIT | Positive | 40 | 56 | 96 | 100% | 7% | 42% | 100% |
Negative | 0 | 4 | 4 | |||||
Total | 40 | 60 | 100 |
Sensitivity = % of patients with anemia, according to the reference laboratory test, that were identified as anemic by the point-of-care test; specificity = % of patients without anemia, according to the reference laboratory test, that were identified as non-anemic by the point-of-care test; PPV, positive predictive value = % of patients that were identified as anemic by the point-of-care test that were confirmed as anemic by the reference laboratory test; NPV, negative predictive value = % of patients that were identified as non-anemic by the point-of-care test that were confirmed as non-anemic by the reference laboratory test.