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. 2016 Apr 5;11(4):e0152184. doi: 10.1371/journal.pone.0152184

Table 1. Phase 2 (community based clinical setting) sensitivity, specificity, and predictive values for the 3 point-of-care tests to detect or exclude anemia.

Females (12 g/dl cut-off)
Point-of-care tests reference
  Outcome Positive Negative Subtotal sensitivity specificity PPV NPV
HemoCue Positive 26 8 34 72% 70% 76% 66%
  Negative 10 19 29
  Total 36 27 63
Stat-Site Positive 30 11 41 83% 59% 73% 73%
  Negative 6 16 22
  Total 36 27 63
URIT Positive 36 25 61 100% 7% 59% 100%
  Negative 0 2 2
  Total 36 27 63
Males (13 g/dl cut-off)
Point-of-care tests reference
  Outcome Positive Negative Subtotal sensitivity specificity PPV NPV
HemoCue Positive 2 10 12 50% 70% 17% 92%
  Negative 2 23 25
  Total 4 33 37
Stat-Site Positive 4 10 14 100% 70% 29% 100%
  Negative 0 23 23
  Total 4 33 37
URIT Positive 4 31 35 100% 6% 11% 100%
  Negative 0 2 2
  Total 4 33 37
Females and males (using the respective cut-off values)
Point-of-care tests reference
  Outcome Positive Negative Subtotal sensitivity specificity PPV NPV
HemoCue Positive 28 18 46 70% 70% 61% 78%
  Negative 12 42 54
  Total 40 60 100
Stat-Site Positive 34 21 55 85% 65% 62% 87%
  Negative 6 39 45
  Total 40 60 100
URIT Positive 40 56 96 100% 7% 42% 100%
  Negative 0 4 4
  Total 40 60 100

Sensitivity = % of patients with anemia, according to the reference laboratory test, that were identified as anemic by the point-of-care test; specificity = % of patients without anemia, according to the reference laboratory test, that were identified as non-anemic by the point-of-care test; PPV, positive predictive value = % of patients that were identified as anemic by the point-of-care test that were confirmed as anemic by the reference laboratory test; NPV, negative predictive value = % of patients that were identified as non-anemic by the point-of-care test that were confirmed as non-anemic by the reference laboratory test.