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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Neuroscientist. 2015 Jan 27;22(2):132–144. doi: 10.1177/1073858414568122

Figure 2.

Figure 2

Nissl stain (A) and expression heat map for CYP46A1 mRNA expression (B) in coronal brain sections of mouse, showing strong neuronal expression. Images are taken from the Allen Brain Atlas, ©2014 Allen Institute for Brain Science. Allen Mouse Brain Atlas, available from http://mouse.brainmap.org/. C. Schematic of neuronal production of 24S-HC from endoplasmic reticulum and subsequent release. For simplicity, interaction of 24S-HC with only two targets is shown: LXR/RXRs of neurons and astrocytes and NMDARs on neuronal plasma membrane.