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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Thromb Res. 2015 Nov 19;140:132–139. doi: 10.1016/j.thromres.2015.11.023

Table 1. Correlation coefficients between TPH or TTP and remaining TG, FG and FL parameters for TF-activated coagulation in normal plasma.

Spearman’s rank correlation coefficient for both time and power parameters with respect to thrombin peak height (TPH, top part of the table) and time to thrombin peak (TTP, lower half of the table). Number in parenthesis indicates significance factor. Correlation coefficients with absolute values closer to 1 show better correlation (+1 = positive correlation; −1 = negative [inverse] correlation). Negative correlations are shown in blue.

TPH vs. TG parameters FG parameters FL parameters
TG velocity TG lag time TG AUC FG velocity Clot time Clot density FL velocity Lysis time FG AUC
tPA:
0.03 μg/ml 0.98 (3.3e-5) −0.90 (0) 0.88 (0) 0.90 (0) −0.98 (3.3e-5) 0.90 (0) 0.98 (3.3e-5) −0.90 (0) 0.88 (0)
0.13 μg/ml 0.90 (0) −0.98 (3.3e-5) 0.95 (2.6e-4) 0.88 (0) −0.93 (8.6e-4) 0.76 (0) 0.71 (0.1) −0.98 (3.3e-5) 0.90 (0)
0.54 μg/ml 1.00 (0) −0.93 (8.6e-4) 0.98 (3.3e-5) 0.90 (0) −0.98 (3.3e-5) 0.38 (0.4) −0.64 (0.1) −0.48 (0.2) 0.83 (0)
2.33 μg/ml 0.98 (3.3e-5) −0.98 (3.3e-5) 0.90 (0) 0.81 (0) −0.90 (0) −0.64 (0.1) 0.21 (0.6) 0.81 (0) 0.60 (0.1)
TTP vs. TG parameters FG parameters FL parameters
TG velocity TG lag time TG AUC Time to FG velocity Clot time Clot density FL velocity Lysis time FG AUC
tPA:
0.03 μg/ml −0.83 (0) 1.00 (0) −0.98 (3.3e-5) 0.98 (3.3e-5) 1.00 (0) −0.86 (0) 0.24 (0.57) 0.95 (2.6e-4) −0.98 (3.3e-5)
0.13 μg/ml −0.93 (8.6e-4) 1.00 (0) −0.98 (3.3e-5) 1.00 (0) 1.00 (0) −0.81 (0) 0.60 (0.12) 1.00 (0) −0.95 (2.6e-4)
0.54 μg/ml −0.93 (8.6e-4) 1.00 (0) −0.98 (3.3e-5) 1.00 (0) 1.00 (0) −0.40 (0.3) 0.98 (3.3e-5) 0.95 (2.6e-4) −0.93 (8.6e-4)
2.33 μg/ml −0.93 (8.6e-4) 1.00 (0) −0.93 (8.6e-4) 1.00 (0) 1.00 (0) 0.62 (0.1) 0.95 (2.6e-4) 0.71 (0.1) −0.62 (0.1)