Table 1.
Demographics of participants of the EAGeR cohort achieving a clinically confirmed pregnancy
| Characteristics | Total | Low AMH <1.0 ng/ml | Normal AMH 1.0-3.5 ng/ml | High AMH >3.5 ng/ml | P Valuea |
|---|---|---|---|---|---|
| n (%) | 708 | 73 (10.3) | 346 (48.9) | 289 (40.8) | |
| Age, y | 28.7 ± 4.6 | 32.6 ± 4.8 | 29.0 ± 4.6 | 27.3 ± 3.9 | <0.001 |
| BMI, kg/m2 | 25.5 ± 6.1 | 25.6 ± 6.4 | 25.6 ± 6.2 | 25.2 ± 5.8 | 0.70 |
| Race | 0.78 | ||||
| White | 685 (96.8) | 72 (98.6) | 334 (96.5) | 279 (96.5) | |
| Non-White | 23 (3.2) | 1(1 .4) | 12 (3.5) | 10(3.5) | |
| Marital status | 0.78 | ||||
| Living with partner | 25 (3.5) | 4 (5.5) | 10 (2.9) | 11 (3.8) | |
| Married | 672(94.9) | 69 (93.2) | 330 (95.4) | 274 (94.8) | |
| Other | 11 (1.6) | 1(1.4) | 6 (1.7) | 4 (1.4) | |
| > High School Education | 636 (89.8) | 62(84.9) | 317 (91.6) | 257 (88.9) | 0.18 |
| Treatment | |||||
| Placebo | 342 (48.3) | 30 (41.1) | 174 (50.3) | 138 (47.8) | 0.35 |
| Low Dose Aspirin | 366 (51.7) | 43 (58.9) | 172 (49.7) | 151 (52.2) | |
| Parity | 0.05 | ||||
| Nulliparous | 295 (41.7) | 30 (41.1) | 129 (37.3) | 136 (47.1) | |
| Parous (1 or 2 prior live births) | 413 (58.3) | 43 (58.9) | 217 (62.7) | 153 (52.9) | |
| Number of previous pregnancy losses | 0.57 | ||||
| 1 | 470 (66.4) | 50 (68.5) | 223 (64.5) | 197 (68.2) | |
| 2 | 238 (33.6) | 23 (31.5) | 123 (35.5) | 92 (31.8) | |
| Gestational age of most recent loss, wks | 9.3 ± 4.7 | 9.7 ± 5.1 | 9.3 ± 4.6 | 9.2 ± 4.8 | 0.74 |
| Time from last loss to randomization | 0.06 | ||||
| ≤ 4 months | 419 (60.4) | 50 (69.4) | 203 (60.1) | 166 (58.5) | |
| 5-8 months | 126 (18.2) | 10 (13.9) | 51 (15.1) | 65 (22.9) | |
| 9-12 months | 48 (6.9) | 5 (6.9) | 26 (7.7) | 17 (6) | |
| >12 months | 101 (14.6) | 7 (9.7) | 58 (17.2) | 36 (12.7) |
a
P -values based on Analysis of Variance (ANOVA) test for continuous variables, and χ2 test (or Fisher's exact test when cell count <5) for categorical variables. Information was missing for BMI (n=9), gestational age of most recent loss (n=94), time from last loss to randomization (n=14).