Table 2. Ligand-binding affinities.

	Kd (nM)
WT-E2	0.26 ± 0.13
Y537S-E2	1.43 ± 0.55
D537G-E2	1.30 ± 0.63
	Ki (nM)
WT-TOT	0.337 ± 0.018
Y537S-TOT	2.61 ± 0.60
D538G-TOT	3.42 ± 0.50