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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Exp Clin Psychopharmacol. 2016 Feb;24(1):55–64. doi: 10.1037/pha0000058

Figure 2.

Figure 2

Cue-induced reinstatement to cocaine seeking in female rats following oxytocin pretreatment. (A) Active lever responding during acquisition of self-administration. (B) Active lever responding during extinction. (C) Active lever responding during reinstatement. Oxytocin (1 mg/kg) significantly decreased active lever responding as compared to vehicle (p < 0.05). (D) Active lever responding during reinstatement by estrous cycle and effective dose of oxytocin. No effect of cycle phase was seen during cue-induced reinstatement. *significant difference from vehicle, p < 0.05