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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Methods. 2015 Oct 6;99:81–90. doi: 10.1016/j.ymeth.2015.10.002

Fig 2. The formation of SC niche within engineered muscle tissue.

Fig 2

Left, activated SCs, when embedded in a myoconductive 3D environment, will rapidly fuse. Middle, a subset of the cells will home to the membrane of the developing myotubes, link to M-cadherin, and cease to proliferate. Right, with time, the SCs will further build their niche on the mature myofiber by homing beneath the basal lamina, expressing M-cadherin, and becoming quiescent.