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Percentage cytotoxicity and hemolysis of 12 selected hits. (A) Cytotoxicity was assessed using Caco-2 cells exposed to 1 μL of compound (200 μM) for 24 h. (B) The percentage hemolysis was determined by using fresh heparinized sheep blood RBCs incubated with 1 μL of compound (200 μM) for 1 h. All compounds showed significantly less cytotoxicity (P ≤ 0.001) compared to positive control.
