Table 1.

Summary of classes of top 12 small molecule compounds identified as anti-campylobacter agents.

		C. jejuni		C. coli		Resistance				In vitro
Class	Compound number	MICa (μM)	MBCb (μM)	MIC (μM)	MBC (μM)	Single step 5X MIC	Passage 0.5X MIC	Cytotoxicity (%)	Hemolysis (%)	Concentration (μM)
Piperazine	Comp 5	50	50	50	50	No	No	6.5	0	>200
	Comp 2	100	100	50	100	No	No	6.9	0	>200
	Comp 4	50	50	50	100	No	No	4.6	0	>200
	Comp 3	12.5	25	50	50	No	No	11.3	0	>200
Piperidines	Comp 18	25	25	200	>200	No	No	8.8	0	100
	Comp 22	12.5	25	100	100	No	No	12.1	0	100
Aryl amines	Comp 17	12.5	25	50	50	No	No	16.6	0	>200
	Comp 10	50	50	100	100	No	No	27.8	0	50
	Comp 13	12.5	25	50	50	No	No	0	0	>200
	Comp 12	100	100	50	100	No	No	0	0	100
Sulfonamide	Comp 1	50	50	50	50	No	No	30.3	7.4	200
Pyridazinone	Comp 7	12.5	12.5	50	50	No	No	28.0	0	25

^aMinimum inhibitory concentration.

^bMinimum bactericidal concentration.