Table 1. OSNs discrimination and behaviour response to Panel 1 odorants.
| Odorant pairs | Changes | Co-activation | Exclusion (%) | Behaviour |
|---|---|---|---|---|
| [1] versus [2] | C–>S, polarity and ring size change | 72%/66% | 30 | Habituated |
| [1] versus [3] | C–>O, polarity, ring size and TPSA changes | 25%/41% | 69 | Dishabituated** |
| [1] versus [4] | C–>N, polarity and ring TPSA change | 38%/55% | 71 | Dishabituated* |
| [1] versus [5] | C–>S, C–>N, dipolarity, ring size and TPSA changes | 30%/49% | 55 | — |
| [1] versus [6] | C–>N (2 × ), ring TPSA changes | 13%/29% | 74 | Dishabituated* |
| [2] versus [3] | S–>O, polarity and ring TPSA changes | 30%/53% | 62 | — |
| [2] versus [4] | Polarity, ring size and TPSA changes | 35%/55% | 57 | — |
| [2] versus [5] | C–>N, dipolarity and ring TPSA change | 37%/65% | 53 | Dishabituated** |
| [2] versus [6] | Polarity, ring size and TPSA changes | 16%/37% | 81 | — |
| [3] versus [4] | Polarity, ring size change | 43%/38% | 60 | Dishabituated* |
| [3] versus [5] | O–>N, C–>S, dipolarity | 40%/40% | 60 | — |
| [3] versus [6] | Ring size and TPSA changes | 23%/30% | 73 | — |
| [4] versus [5] | C–>S, dipolarity, ring size change | 42%/47% | 55 | Habituated |
| [4] versus [6] | C–>N, polarity, ring size and TPSA changes | 26%/39% | 68 | — |
| [5] versus [6] | Dipolarity, ring size and TPSA changes | 33%/44% | 62 | Habituated |
TPSA, topological polar surface area.
This table recapitulates co-activation among the OSNs and behavioural responses observed with Panel 1 odorant pairs. ‘Changes' gives the substitutions and transformations from one odorant to the other. The first co-activation number gives the percentage of OSNs responding to the first odorant of the pair that were co-activated by the second odorant. The second co-activation number gives the percentage of OSNs responding to the second odorant of the pair that were co-activated by the first odorant. ‘Exclusion' numbers give the percentage of OSNs that respond exclusively to one odorant of the pair among the total number of OSNs that respond to those two odorants. ‘Behaviour' recapitulates the results observed during the habituation/dishabituation olfactory tests with the odorants of the pair. Behaviour results were analysed using ANOVA test followed by a post hoc paired t-test (*P<0.05, **P<0.005 paired post hoc t-test).