Table 1. Clinical features of each patient.

Case no.	Age	Sex	T	N	PathR	Mandard
1	69	Male	2	0	Yes	3
2	78	Male	3	1	Yes	3
3	49	Male	3	1	Yes	3
4	53	Male	2	1	Yes	3
5	73	Male	3	0	Yes	2
6	63	Male	2	0	Yes	2
7	68	Male	3	1	Yes	3
8	54	Male	3	0	Yes	2
9	58	Female	2	0	Yes	3
10	61	Male	1	1	Yes	3
11	71	Male	3	1	No	4
12	56	Female	3	1	No	5
13	67	Male	2	1	No	4
14	62	Male	3	1	No	4
15	67	Male	2	1	No	4
16	60	Male	3	1	No	4
17	77	Male	3	1	No	5
18	68	Female	2	0	No	5
19	65	Male	2	3	No	4
20	65	Male	3	1	Yes	3
21	70	Male	3	1	No	4
22	60	Male	3	0	Yes	3
23	73	Male	3	0	Yes	3
24	57	Male	1	1	No	5
25	65	Female	3	1	No	4
26	76	Male	2	0	No	4
27	78	Female	4	0	Yes	3
28	74	Male	2	0	Yes	3
29	29	Male	3	0	No	5
30	69	Female	3	1	No	4

T, N AJCC tumour and node stage; PathR, binary pathological response derived from Mandard score, Mandard, Mandard response grade. Further details are provided in Supplementary Table 1.