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. 2016 Apr 6;6:24045. doi: 10.1038/srep24045

Table 1. Hematological parameters in male and female mice fed a low or normal iron diet.

  Male
Female
Low iron diet
Normal diet
Low iron diet
Normal diet
Wild type Ndfip2−/− Wild type Ndfip2−/− Wild type Ndfip2−/− Wild type Ndfip2−/−
Hemoglobin (g/L) 104.4 ± 11.5 111.0 ± 10.6 122.0 ± 6.7 125.4 ± 9.3 102.3 ± 1.5 113.2 ± 11.8 126.0 ± 8.1* 128.1 ± 5.8*
RBC count (x1012/L) 8.7 ± 0.3 8.9 ± 0.5 7.5 ± 0.3* 7.7 ± 0.7* 8.6 ± 0.3 8.9 ± 0.3 7.9 ± 0.5* 8.1 ± 0.4*
Hematocrit (%) 35.0 ± 3.0 37.0 ± 4.0 39.0 ± 1.0 40.0 ± 4.0 34.7 ± 1.2 38.0 ± 4.1 41.2 ± 1.7* 41.1 ± 1.5*
MCV (fl) 41.2 ± 2.4 41.3 ± 2.6 52.2 ± 1.0* 52.2 ± 0.9* 40.5 ± 2.2 42.8 ± 4.2 52.3 ± 1.1* 51.1 ± 0.9*
MCH (pg) 12.3 ± 0.7 12.4 ± 0.7 16.2 ± 0.4* 16.3 ± 0.9* 11.9 ± 0.5 12.8 ± 1.2 16.0 ± 0.1* 15.9 ± 0.2*
MCHC (g/L) 299.4 ± 9.5 302.0 ± 6.2 310.8 ± 10.9 313.0 ± 19.9 294.7 ± 3.5 298.8 ± 7.1 306.8 ± 7.4* 310.9 ± 5.6
RDW (%) 22.5 ± 2.7 21.9 ± 1.6 16.4 ± 1.1* 16.3 ± 1.0* 22.3 ± 1.0 22.1 ± 1.7 15.9 ± 0.2* 15.9 ± 1.2*

There are no significant differences in any of these parameters between wild type and knockout mice, or between males and females on any diet. *represents significant differences between low iron and normal diets within genders and genotypes. Data expressed as mean ± s.d.; n = 3–8. RBC; red blood cell; MCV, mean corpuscular volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; RDW, red cell distribution width.