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. 2016 Apr 6;6:23634. doi: 10.1038/srep23634

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Black dashed lines represent H-bonds between the flavonoids and the protein active site residues. (a) the interactions between 13 flavonoids and the surface of the pocket on GyrB (MOE); (b) the binding orientations of 13 flavonoids (SYBYL X-2.0) 13 flavonoids are 5, 6, 7, 8, 9, 11, 12, 13,14, 15, 17, 21 and 29.