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. 1979 Dec;42(6):742–745. doi: 10.1136/hrt.42.6.742

Congenital cardiac abnormalities in monozygotic twins. Report and review of the literature.

S F Seides, R J Shemin, A G Morrow
PMCID: PMC482231  PMID: 575295

Abstract

A pair of monozygotic twin girls is reported with concordance for 3 congenital cardiac abnormalities: (1) secundum atrial septal defect, (2) aneurysm of the membraneous ventricular septum, and (3) electrocardiographic frontal plane left axis deviation. A review of the published materials shows a 9.5 per cent incidence of concordance for congenital heart disease among monozygotic twins. In those in whom a precise cardiological diagnosis was made, 15/16 pairs (95%) were concordant for a specific defect, 2 had an additional defect, and only 1 pair had completely dissimilar defects. Concordance for congenital heart disease in monozygotic twins is uncommon, but when it occurs the defects will most often be identical.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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