Table 1.
Patient characteristics
| Pt# | A/S | Tumor Type | Tumor Location | Total dose/Fx | Dmean(range) LH** | Dmean(range) RH** |
|---|---|---|---|---|---|---|
| 1* | 43/M | Grade 2 Gemistocytic Astrocytoma | Right Temporal | 59.4/1.8 | 15.2(11.7–24.4) | 53.8(49.5–54.9) |
| 2* | 64/M | Sphenoid Wing Meningioma | Left Temporal, Petrous ridge | 54/1.8 | 51.3(38.4–53.6) | 39.7(18.9–49.1) |
| 3 | 80/M | Pituitary Macroadenoma | Suprasellar | 50.4/1.8 | 23.4(7.6–42.8) | 28.2(8.8–44.7) |
| 4* | 47/M | Grade 2 mixed Oligoastrocytoma | Right Frontal, Temporal | 59.4/1.8 | 31.6(22.5–44.4) | 55.5(50.7–57.5) |
| 5 | 38/M | Craniopharyngioma | Suprasellar | 55.8/1.8 | 31.3(7.9–51.7) | 31.5(4.1–51.6) |
| 6* | 38/M | Grade 2 diffuse Astrocytoma | Left Frontal, Temporal | 54/1.8 | 51.4(50.8–52.2) | 46.2(35.9–50.3) |
| 7* | 43/M | Grade 3 Anaplastic Supratentorial Ependymoma | Left Frontal | 59.4/1.8 | 53.2(37.2–59.7) | 24.3(18.3–37.1) |
| 8 | 52/M | Pituitary Null-cell Adenoma | Suprasellar | 50.4/1.8 | 26.5(1.9–46.5) | 22.1(1.8–47.3) |
| 9 | 51/M | Pituitary Macroadenoma | Suprasellar | 50.4/1.8 | 12.3(1.05–43.6) | 23.7(1.57–47.4) |
| 10* | 32/F | Grade 2 Glioma | Left Frontal, Temporal | 54/1.8 | 55.2(49.7–59.3) | 14.4(8.97–20.9) |
| 11 | 70/M | Pituitary Macroadenoma | Suprasellar | 50.4/1.8 | 23.2(2.08–44.7) | 26.9(2.97–46.4) |
| 12 | 62/M | Grade 2 Astrocytoma | Left Frontal | 54/1.8 | 39.8(22.3–51.7) | 29.4(15.4–39.7) |
| 13 | 64/F | Pituitary Null-cell Adenoma | Suprasellar | 50.4/1.8 | 11.9(1.1–36.7) | 19.1(0.9–46.6) |
| 14 | 57/F | Meningioma | Left Temporal, Parasellar | 54/1.8 | 34.1(1.64–56) | 23.9(1.45–53.7) |
| 15* | 31/F | Low grade Glioma | Left Frontal | 54/1.8 | 54.3(45.4–56.3) | 20.1(18.1–24.5) |
| 16 | 60/M | Pituitary Null-cell Adenoma | Suprasellar | 50.4/1.8 | 19.3(0.8–49.7) | 11.7(0.7–46.8) |
| 17 | 48/F | Pituitary Null-cell Adenoma | Suprasellar | 50.4/1.8 | 4.4(0.9–29.6) | 7(1–42) |
| 18 | 48/M | Grade 2 diffuse Oligodendroglioma | Right Parietal | 54/1.8 | 3.6(1.6–15.1) | 23.6(9–53.2) |
| 19 | 50/F | Pituitary Macroadenoma | Suprasellar | 50.4/1.8 | 7.6(0.4–41.3) | 9.4(0.5–40.1) |
| 20 | 57/F | Meningioma | Left Parietal, Parasagittal | 54/1.8 | 2(1.1–7) | 4.2(1.4–11.4) |
| 21 | 58/F | Grade 2 Gemistocytic Astrocytoma | Left Frontal | 54/1.8 | 16.5(8.9–26.2) | 6.1(3.1–8.5) |
| 22 | 50/M | Pituitary Macroadenoma | Suprasellar | 50.4/1.8 | 8.6(1.3–20.5) | 12.2(2.7–30.9) |
| 23 | 40/F | Meningioma | Left Occipital, Tentorial and Posterior Fossa | 54/1.8 | 8.4(2.5–13.4) | 3.4(2.1–4.5) |
| 24 | 50/M | Meningioma | Right Cavernous sinus | 54/1.8 | 8.2(1.14–21.1) | 14.2(1.2–55.1) |
| 25* | 51/M | Grade 2 diffuse Astrocytoma | Left Temporal, Parietal | 59.4/1.8 | 56.1(55.2–57.5) | 16.8(15–18.8) |
| 26 | 48/M | Pituitary Null-cell Adenoma | Suprasellar | 54/1.8 | 17.5(1.2–49.3) | 38.6(1.6–55.2) |
| 27 | 32/F | Pituitary Craniopharyngioma | Suprasellar | 55.8/1.8 | 11.3(0.9–42.3) | 13.42(0.9–49.6) |
Abbreviations: Pt # = Patient number; A/S = Age/Sex; M = Male; F = Female; Dmean = mean radiation dose in the hippocampus; LH = left hippocampus; RH = right hippocampus; Fx = fraction size.
*
Hippocampus is affected by either tumor or edema.
**
2-Gy equivalent dose by the linear-quadratic equation with a/β = 2.5Gy.