The associations (Rs) between rectal morbidity and the dDVHs given the 0.02 increase criterion in the Rs-value for the dDVH compared to the Rs-value for the pDVH, summarised for isotropic and anisotropic motion with σ = 0.2, 0.5 and 0.8 cm given for the dose levels (Gy) investigated. The increase in associations was seen especially at intermediate doses (45-60 Gy). Isotropic motion provided stronger associations also at low doses (≤ 20 Gy). Applying anisotropic random motion, the associations were stronger also at high doses (≥ 60 Gy).