. Author manuscript; available in PMC: 2016 Oct 1.

Published in final edited form as: J Pharm Sci. 2015 Jul 6;104(10):3426–3439. doi: 10.1002/jps.24551

Table 3.

In Vitro Efficacy of IQP-0528 and SAMT-10 Against HIV-1.

Compound	CEM-SS/HIV-1_IIIB		PBMCs/HIV-1_ZA/97/009		HIV-1_RF Cell to Cell Transmission
Compound	EC₅₀ (µM)	EC₉₅ (µM)	EC₅₀ (µM)	EC₉₅ (µM)	EC₅₀ (µM)	EC₉₅ (µM)
IQP-0528	0.002	0.008	0.006	0.019	0.006	0.085
SAMT-10	0.73	2.9	8.2	>9.6	0.53	9.1

Efficacy of IQP-0528 and SAMT-10 in standard HIV-1 cell based efficacy assays. Calculated EC₅₀ and EC₉₅ values are the average of two or three independent experiments. Within each experiment each compound concentration was evaluated in triplicate.