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SPR effects on SM function in cotransfection assays. 293 cells were transfected with SM-responsive EBV genes (BILF2, BDLF1) or SM-independent genes (EBER2, ZTA) cloned in an expression vector with either empty vector (C) or SM. SM-transfected cells were treated with either vehicle (SM) or SPR (SM +S). RNA was harvested 28 h posttransfection, and gene expression was measured by RNA qPCR. RQ, relative quantity of RNA.
