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Plasma HbA1c after treatment of ZDF rats with ND-630
| Dose, b.i.d., p.o. mg/kg | HbA1c, % of total Hb | P value | Reduction, % of total Hb |
| Vehicle | 10.2 ± 0.3 | – | – |
| 0.5 | 9.8 ± 0.4 | 0.52 | 0.4 |
| 1.5 | 9.7 ± 0.2 | 0.47 | 0.5 |
| 5.0 | 9.3 ± 0.2 | 0.029 | 0.9 |
Plasma HbA1c levels were determined on day 37 of the study 1 h after the final dose. Hb, hemoglobin.
