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Bcl-2 family protein binding to InsP3R peptides. (A) Quantification of Bcl-xL binding to various InsP3R C-terminal peptides, normalized to Bcl-xL in lysate. Mean ± SEM, n = 3, **P < 0.01; ***P < 0.001. Related to Fig. 1. (B) BH3-like domain-containing InsP3R peptides bind to Bcl-xL (Left) or Mcl-1 (Right) with efficacies equal to those of the full-length helices. Related to Fig. 2.
