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Regulation of pulmonary vascular tone by potassium channels. Acute contraction of PASMCs is activated, in part, by a potassium (K+) inhibition-induced membrane depolarization and subsequent Ca2+ entry through nifedipine-sensitive L-type Ca2+ channels. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars
