Table 4. .
Multivariable-adjusted difference in 24-hour urinary phosphorus excretion and fractional excretion of phosphorus per 10% higher percentage African ancestry among African-American participants in the CRIC study
| 24-hour urine phosphorus excretion | Fractional excretion of phosphorus | |||||||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 1 | Model 2 | |||||
| Variables | mg/day (95%CI) | P value | mg/day (95%CI) | P value | % (95%CI) | P value | % (95%CI) | P value |
| African ancestry, per 10% higher | −36.4 (−19.0, −53.7) | <0.001 | −39.6 (−18.2, −60.9) | <0.001 | −1.0 (−0.2, −1.8) | 0.009 | −1.1 (−0.2, −2.0) | 0.01 |
| Age, per 1 year | −3.1 (−1.6, −4.7) | <0.001 | −2.4 (−0.4, −4.4) | 0.02 | −0.1 (−0.0, −0.2) | 0.007 | −0.2 (−0.1, −0.3) | <0.001 |
| Female sex | −136.3 (−104.3, −168.2) | <0.001 | −147.2 (−105.1, −189.2) | <0.001 | −4.9 (−3.4, −6.3) | <0.001 | −3.9 (−2.2, −5.7) | <0.001 |
| eGFR, 1 ml/min per 1.73 m2 | 2.7 (1.7,3.7) | <0.001 | 2.7 (1.3,3.9) | <0.001 | −0.4 (−0.3, −0.4) | <0.001 | −0.4 (−0.3, −0.5) | <0.001 |
| Body mass index, per 1 kg/m2 | 6.3 (3.7,8.9) | <0.001 | −0.1 (−0.0, −0.2) | 0.19 | ||||
| Diabetes | 11.2 (−31.3,53.6) | 0.61 | 1.3 (−0.4,3.1) | 0.14 | ||||
| Education < versus ≥ high school diploma | 28.6 (−22.5,79.7) | 0.27 | 2.7 (0.5,4.9) | 0.01 | ||||
| Annual income ≤ versus > $20,000/year | −73.5 (−30.4, −116.7) | <0.001 | −0.1 (−1.9,1.8) | 0.95 | ||||
| Dietary phosphorus, per 100 g/day | 7.4 (3.74,11.1) | <0.001 | 0.3 (0.2,0.5) | <0.001 | ||||
| Serum phosphorus, per 1 mg/dL | 45.8 (11.3,80.3) | 0.01 | −4.2 (−2.8, −5.7) | <0.001 | ||||
Analyses restricted to 1393 African-American participants with plausible 24-hour urine data.