Fig. 1.

Forest plot showing the pooled OR for making a genetic diagnosis of HNF1B-related disease for different clinical features in the paediatric (a) and the adult cohorts (b) of the combined referrals for HNF1B genetic testing to both Exeter, UK and Toulouse, France (n = 1,119). Other renal abnormalities include multicystic dysplastic kidney, urinary tract malformations, single kidney and glomerular cysts/oligomeganephronia on biopsy. CI = Confidence interval; DM = diabetes mellitus; HNF1B = hepatocyte nuclear factor 1β; OR = odds ratio.