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. Author manuscript; available in PMC: 2017 Feb 22.
Published in final edited form as: Curr Biol. 2016 Feb 4;26(4):542–549. doi: 10.1016/j.cub.2015.12.055

Figure 3. Coordinated Regulation of ECM Assembly by Cdh2 and Itgα5.

Figure 3

(A and B) Lateral (A) and dorsal (B) views of the anterior paraxial mesoderm in 10- to 12-somite-stage embryos showing loss of somite borders and de-adhesion of cells in MZitgα5−/−;cdh2mo embryos (n = 8).

(C) 3D dorsal projection of anterior paraxial mesoderm FN immunolocalization z stacks showing loss of dorsolateral FN in MZitgα5−/−;cdh2mo embryos.

(D) Single dorsal z-slices of FN immunolocalization of posterior paraxial mesoderm showing globular FN in cdh2mo embryos and diffuse ectopic FN in MZitgα5−/−;cdh2mo embryos.

Scale bars, 40 μm.