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Primary and tertiary structures of cyclotides from the Möbius (kalata B1, pdb code: 1NB1), bracelet (cycloviolacin O1, pdb code: 1NBJ) and trypsin inhibitor (MCoTI-II, pdb code: 1IB9) subfamilies. The sequence of kalata B8, a novel hybrid cyclotide isolated from the plant O. affinis is also shown. Conserved cysteine residues are marked in yellow and disulfide connectivities in red. The circular backbone topology is shown with a blue line.
