Table 1. Clinical parameters and level of sCD155 in healthy donors and cancer patients.
Number (male/female) | Mean age | Stage 0/I/II/III/IV/unk | sCD155 level (ng/mL) | P value | ||||
---|---|---|---|---|---|---|---|---|
Mean | Median | Range | ||||||
Healthy controls | 60 (29/31) | 57.8 | - | 15.6 | 15.3 | 4.6–30.9 | - | |
All cancer patients | 262 (122/140) | 63.2 | 28.3 | 22.8 | 0.3–168.5 | <0.0001 | ||
Lung cancer | 52 (35/17) | 68.5 | 2/36/ 7/ 4/ 3/ 0 | 23.2 | 19.1 | 0.3–97.7 | <0.05 | |
Esophageal cancer | 8 (8/0) | 69.9 | 0/ 0/ 3/ 2/ 3/ 0 | 35.3 | 26.1 | 11.8–111.0 | <0.001 | |
Gastric cancer | 49 (37/12) | 66.5 | 0/19/ 5/ 5/20/ 0 | 25.0 | 20.6 | 8.7–73.8 | <0.0001 | |
Colorectal cancer | 12 (4/8) | 63.6 | 0/ 0/ 1/ 4/ 7/ 0 | 32.0 | 25.2 | 7.5–95.7 | <0.001 | |
Bile-duct cancer | 25 (16/9) | 72.0 | 0/ 1/ 1/ 1/17/ 5 | 39.5 | 39.9 | 14.7–77.9 | <0.0001 | |
Pancreatic cancer | 18 (14/4) | 62.1 | 0/ 0/ 0/ 1/17/ 0 | 46.4 | 27.2 | 11.1–168.5 | <0.0001 | |
Breast cancer | 32 (0/32) | 53.6 | 2/10/12/ 4/ 4/ 0 | 21.3 | 20.5 | 4.2–50.6 | <0.05 | |
Ovarian cancer | 23 (0/23) | 57.7 | 0/12/ 1/ 7/ 3/ 0 | 26.2 | 23.2 | 4.8–125.3 | <0.01 | |
Endometrial cancer | 16 (0/16) | 59.5 | 0/10/ 1/ 3/ 2/ 0 | 26.3 | 24.6 | 4.6–71.6 | <0.01 | |
Cervical cancer | 15 (0/15) | 49.6 | 0/ 4/ 6/ 4/ 1/ 0 | 19.6 | 20.4 | 7.5–39.6 | NS | |
Others | 12 (8/4) | 63.8 | 41.0 | 22.9 | 0.6–167.9 | <0.05 |
Abbreviations: NS, not significant. Unk, unknown.