. Author manuscript; available in PMC: 2016 Sep 1.

Published in final edited form as: Mov Disord. 2015 Jun 11;30(10):1371–1381. doi: 10.1002/mds.26248

Table 4. Biologics data.

Variable	PD Subjects	Healthy Controls	P Value^a	PD Subjects ESS +	PD Subjects ESS-	P Value^a	Controls ESS +	Controls ESS -	P Value^a
	(n = 423)	(n = 196)	(PD vs. HC)	(n = 66)	(n = 357)	(PD ESS+ vs. −)	(n = 24)	(n = 171)	(HC ESS + vs. −)
A-Beta			0.39			0.02			0.13
Mean	370.56	377.77		345.49	375.09		401.74	374.45
(Min, max)	(129.20, 796.50)	(88.80, 879.50)		(147.80, 670.00)	(129.20, 796.50)		(292.60, 559.30)	(88.80, 879.50)
Missing	11	7		3	8		2	5
T-Tau			<0.01			0.62			0.16
Mean	44.69	52.54		47.45	44.19		47.97	53.13
(Min, max)	(14.40, 121.00)	(18.40, 223.10)		(15.40, 117.00)	(14.40, 121.00)		(21.50, 117.10)	(18.40, 223.10)
Missing	15	9		3	12		2	7
P-Tau			<0.01			0.17			0.84
Mean	15.64	18.27		13.82	15.96		18.21	18.32
(Min, max)	(4.70, 94.10)	(5.10, 73.30)		(4.70, 42.60)	(5.70, 94.10)		(6.40, 50.00)	(5.10, 73.30)
Missing	13	7		4	9		2	5
T-Tau/A-Beta			0.02			0.08			0.03
Mean	0.13	0.16		0.15	0.12		0.11	0.17
(Min, max)	(0.04, 0.52)	(0.05, 2.12)		(0.06, 0.49)	(0.04, 0.52)		(0.07, 0.21)	(0.05, 2.12)
Missing	15	9		3	12		2	7
P-Tau/A-Beta			0.01			0.45			0.72
Mean	0.04	0.06		0.04	0.04		0.04	0.06
(Min, max)	(0.01, 0.51)	(0.02, 0.66)		(0.02, 0.15)	(0.01, 0.51)		(0.02, 0.10)	(0.02, 0.66)
Missing	13	7		4	9		2	5
P-Tau/T-Tau			0.52			0.01			0.19
Mean	0.37	0.37		0.32	0.38		0.42	0.36
(Min, max)	(0.08, 2.14)	(0.13, 1.40)		(0.08, 1.08)	(0.12, 2.14)		(0.13, 0.79)	(0.14, 1.40)
Missing	17	9		4	13		2	7
Alpha-Synuclein			<0.01			0.19			0.31
Mean	1844.68	2204.25		2031.93	1810.88		1959.26	2234.76
(Min, max)	(332.93, 6694.55)	(592.56, 8608.91)		(665.54, 6694.55)	(332.93, 5174.16)		(829.31, 3948.40)	(592.56, 8608.91)
Missing	11	7		3	8		2	5

P values from Mann-Whitney U tests.