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. 2015 Oct 16;7(3):2433–2454. doi: 10.18632/oncotarget.5693

Figure 6. A model connecting BRCA1/2 mutations, telomere perturbations and malignant transformation.

Figure 6

This model summarizes the possible connection between BRCA1/2 mutation leading to perturbations in telomere length homeostasis and susceptibility to malignant transformation. The model is described in more details in the Discussion section.