Table 1. Prognostic impact of FAM83D expression level in 18 possible pools corresponding to every combination of populations (nodal and ER status).

LN	ER	Event status	p-value	Hazard ratio	95% CI	No patients	No events
Nm	Erm	AE	< 0.0001	1.34	1.26 - 1.43	2653	909
Nm	ER+	MR	< 0.0001	1.56	1.41 - 1.71	1198	282
Nm	ERm	MR	< 0.0001	1.44	1.33 - 1.56	1672	425
Nm	ER+	AE	< 0.0001	1.42	1.31 - 1.54	1897	624
N+	ERm	MR	< 0.0001	1.56	1.36 - 1.80	439	166
N+	ER+	MR	< 0.0001	1.63	1.38 - 1.92	343	118
N-	ERm	AE	< 0.0001	1.38	1.23 - 1.55	1048	299
N-	ER+	AE	< 0.0001	1.5	1.29 - 1.75	743	213
N+	ERm	AE	< 0.0001	1.29	1.17 - 1.43	911	406
N-	ER+	MR	< 0.0001	1.78	1.41 - 2.27	422	78
N+	ER+	AE	< 0.0001	1.33	1.18 - 1.51	685	284
N-	ERm	MR	0.0001	1.42	1.20 - 1.69	590	111
Nm	ER-	MR	0.0681	1.17	0.99 - 1.38	454	140
Nm	ER-	AE	0.0878	1.12	0.98 - 1.27	727	278
N-	ER-	AE	0.0909	1.23	0.97 - 1.56	285	82
N+	ER-	MR	0.3033	1.16	0.87 - 1.55	94	48
N-	ER-	MR	0.7622	1.06	0.74 - 1.51	153	32
N+	ER-	AE	0.7638	1.03	0.84 - 1.27	223	122

Node or ER status (+: positive, −: negative, m: mixed); AE: any event; MR: metastatic relapse; HR: hazards ratio.