Table 3. Multivariate analysis of significant clinicopathological factors associated with lymph node metastasis of hepatocellular carcinoma in the training cohort.
| Clinicopathological factors | Multivariate | |||
|---|---|---|---|---|
| χ2 score | Hazard ratio | 95% CI | P | |
| Vascular invasion | ||||
| no | 1 | 2.010-13.199 | 0.001* | |
| yes | 11.665 | 5.151 | ||
| BCLC stage | ||||
| 0–A | 1 | 1.204-6.984 | 0.018* | |
| B–C | 5.632 | 2.899 | ||
| MiR-145 | ||||
| negative | 1 | 1.295-10.176 | 0.014* | |
| positive | 6.011 | 3.630 | ||
| MiR-31 | ||||
| negative | 1 | 1.427-8.613 | 0.006* | |
| positive | 7.485 | 3.506 | ||
| MiR-92a | ||||
| negative | 1 | 1.098-10.833 | 0.034* | |
| positive | 4.496 | 3.449 | ||
Variables were adopted for their prognostic significance on univariate analysis.
BCLC stage Barcelona Clinic Liver Cancer stage, CI confidence interval, * significance values.