Table 1. Baseline characteristics of patients included in this study.
| Baseline characteristics | Palliative group (n=74) | GKR group (n=64) | P value* | |
|---|---|---|---|---|
| Age | Mean±SD | 54.34±11.01 | 52.83±9.53 | 0.394 |
| Gender | Male (n=117) | 64 | 53 | 0.549 |
| Female (n=21) | 10 | 11 | ||
| Etiologies | HBV (n=116) | 61 | 55 | 0.722 |
| HCV (n=7) | 4 | 3 | ||
| Alcohol(n=10) | 5 | 5 | ||
| Others(n=5) | 4 | 1 | ||
| Type of PVTT | Branches of portal vein (n=71) | 35 | 36 | 0.294 |
| Main portal vein (n=67) | 39 | 28 | ||
| Cirrhosis | Absent (14) | 9 | 5 | 0.573 |
| Precent (124) | 65 | 59 | ||
| Child–Pugh | A (n=107) | 54 | 53 | 0.167 |
| B7 (n=31) | 20 | 11 | ||
| ECOG PST | 0-1 (n=99) | 49 | 50 | 0.121 |
| 2 (n=39) | 25 | 14 | ||
| Tumor nodules | Single (n=65) | 31 | 34 | 0.187 |
| Multiple (n=73) | 43 | 30 | ||
| Largest tumor size | Mean±SD | 9.79±4.77 | 8.14±3.73 | 0.261 |
| ≤5cm | 15 | 11 | 0.098 | |
| 5-10cm | 25 | 33 | ||
| >10cm | 34 | 20 | ||
| Bilobar | No (n=83) | 41 | 42 | 0.221 |
| Yes (n=55) | 33 | 22 | ||
| AFP | ≤400 ng/ml (n=49) | 25 | 24 | 0.649 |
| >400 ng/ml (n=89) | 49 | 40 | ||
| Total bilirubin | Mean ±SD | 1.12±0.64 | 1.10±0.58 | 0.552 |
| >1.5 mg/dl | 15 | 17 | 0.302 | |
| Albumin | Mean ±SD | 34.77±4.11 | 35.58±4.22 | 0.258 |
| <30 g/L | 13 | 9 | 0.349 | |
| ALT | Mean ±SD | 44.51±19.67 | 43.55±21.51 | 0.274 |
| >40 u/L | 15 | 13 | 0.995 | |
| AST | Mean ±SD | 46.27±20.80 | 42.13±21.10 | 0.248 |
| >40 u/L | 17 | 11 | 0.399 | |
| GTT | Mean ±SD | 178.22±132.03 | 182.31±158.86 | 0.869 |
| >50 u/L | 47 | 36 | 0.385 | |
| INR | Mean ±SD | 1.03±0.19 | 1.06±0.21 | 0.493 |
| ≥1.3 | 5 | 5 | 0.811 | |
| WBC | Mean ±SD | 5.26±1.04 | 5.55±1.14 | 0.119 |
| <4.0×109/L | 5 | 6 | 0.571 | |
| HB | Mean ±SD | 123.9±12.02 | 125.70±17.26 | 0.578 |
| <110 g/L | 8 | 5 | 0.548 | |
| Platelets | Mean ±SD | 110.2±17.59 | 112.05±19.66 | 0.562 |
| ≤100×109/L | 21 | 19 | 0.866 |
*: Intergroup differences in baseline characteristics were analyzed using t-test for continuous data and Chi-Square test or Fisher exact test (for small samples) for categorical variables. P< 0.05 was considered statistically significant. TACE: transarterial chemoembolization; GKR: gamma knife radiosurgery; PVTT: portal vein tumor thrombosis; HBV: hepatitis B virus; HCV: hepatitis C virus; ECOG PST: Eastern Cooperative Oncology Group Performance status; INR: international normalized ratio; AFP: alpha fetal protein; ALT: alanine transaminase; AST: aspartate transaminase; WBC: white blood cell; Hb: hemoglobin; GGT: gamma-glutamyl transpeptidase.