Table 1. Patient characteristics by study group.
| Hypo-AML | Non-hypo-AML | P | |
|---|---|---|---|
| Total patients (N) | 43 | 541 | |
| Female sex, N (%) | 21 (48.8) | 229 (42.3) | 0.42 |
| Median age, y (range) | 56 (20-65) | 46 (15-78) | 0.05 |
| AHD, No. (%) | 10 (23.2) | 43 (8) | 0.02 |
| Median WBC count, ×109/L (range) | 2.2 (0.2-64.4) | 12.6 (0.5-247) | < 0.01 |
| Median HGB level, g/L (range) | 83 (30-142) | 82 (35-134) | 0.8 |
| Median platelet count, ×109/L (range) | 51 (4-306) | 35 (1-374) | 0.42 |
| Median bone marrow cellularity, %(range) | 14 (11-20) | 56 (24-82) | 0.03 |
| Median blasts in bone marrow (%) | 43 (24-85) | 53 (20-96) | 0.53 |
| Cytogenetics, No. (%) Poor Intermediate Favorable |
19 (44.2) 19 (44.2) 5 (11.6) |
209 (38.6%) 275 (50.8%) 57 (10.5%) |
0.72 0.81 0.24 |
| CR, No. (%) | 27 (62.8%) | 303 (56.0%) | 0.48 |
| Median OS, months | 9 | 8 | 0.7 |
| Median DFS, months | 8 | 10 | 0.9 |
Hypo-AML, Hypocellular acute myeloid leukemia; AHD, anterior hematological disease; HGB, hemoglobin; CR, complete remission; OS, overall survival; DFS, disease free survival