Table 3.
Outcome | Betamethasone N=1427 | Placebo N=1400 | RR (95% CI) | P value |
---|---|---|---|---|
Neonatal death | 2 (0.1) | 0 (0.0) | - | 0.50 |
Birth weight - grams | 2637 ± 480 | 2654 ± 484 | 0.32 | |
Less than 10th percentile birth weight | 255 (17.9) | 220 (15.7) | 1.14 (0.96-1.34) | 0.13 |
Gestational age at delivery | 0.10 | |||
≤34 weeks | 213 (15.2) | 193 (13.5) | ||
35 weeks | 386 (27.6) | 394 (27.6) | ||
36 weeks | 568 (40.6) | 609 (42.7) | ||
37-38 weeks | 185 (13.2) | 202 (14.2) | ||
39-40 weeks | 48 (3.7) | 29 (2.0) | ||
Necrotizing enterocolitis | 0 (0.0) | 1 (0.1) | ||
Proven neonatal sepsis | 9 (0.6) | 11 (0.8) | 0.80 (0.33-1.93) | 0.62 |
Grade 3-4 intraventricular hemorrhage | 2 (0.1) | 0 (0.0) | - | |
Hypoglycemia (glucose< 40 mg/dl) | 343 (24.0) | 209 (14.9) | 1.61 (1.38-1.88) | <0.001 |
Time to first feed - hours | 5.5 (1.4-24.6) | 10.0 (1.7-29.3) | 0.004 | |
Intermediate nursery/NICU admission | 593 (41.6) | 627 (44.8) | 0.93 (0.85-1.01) | 0.08 |
Intermediate/NICU stay ≥ 3 days | 470 (32.9) | 518 (37.0) | 0.89 (0.80-0.98) | 0.03 |
Data expressed as N (%) or mean ± SD or median (25th-75th percentile)