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. Author manuscript; available in PMC: 2017 Apr 7.
Published in final edited form as: N Engl J Med. 2016 Feb 4;374(14):1311–1320. doi: 10.1056/NEJMoa1516783

Table 3.

Other Secondary Neonatal Outcomes

Outcome Betamethasone N=1427 Placebo N=1400 RR (95% CI) P value

Neonatal death 2 (0.1) 0 (0.0) - 0.50
Birth weight - grams 2637 ± 480 2654 ± 484 0.32
Less than 10th percentile birth weight 255 (17.9) 220 (15.7) 1.14 (0.96-1.34) 0.13
Gestational age at delivery 0.10
    ≤34 weeks 213 (15.2) 193 (13.5)
    35 weeks 386 (27.6) 394 (27.6)
    36 weeks 568 (40.6) 609 (42.7)
    37-38 weeks 185 (13.2) 202 (14.2)
    39-40 weeks 48 (3.7) 29 (2.0)
Necrotizing enterocolitis 0 (0.0) 1 (0.1)
Proven neonatal sepsis 9 (0.6) 11 (0.8) 0.80 (0.33-1.93) 0.62
Grade 3-4 intraventricular hemorrhage 2 (0.1) 0 (0.0) -
Hypoglycemia (glucose< 40 mg/dl) 343 (24.0) 209 (14.9) 1.61 (1.38-1.88) <0.001
Time to first feed - hours 5.5 (1.4-24.6) 10.0 (1.7-29.3) 0.004
Intermediate nursery/NICU admission 593 (41.6) 627 (44.8) 0.93 (0.85-1.01) 0.08
Intermediate/NICU stay ≥ 3 days 470 (32.9) 518 (37.0) 0.89 (0.80-0.98) 0.03

Data expressed as N (%) or mean ± SD or median (25th-75th percentile)