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Sarcomere-like structures provoked by microgrooves. (A) Sarcomere-like structures in reprogrammed SP3 and SP16 cells, comparing grooved versus flat substrates by confocal imaging for sarc MyHC. Scale bar: 50 μm and insert, 5 μm. (B) Microgrooves induced a 10-fold increase in ordered sarcomeres (*p < 0.05; Student's t-test, n = 63, error bars indicate standard deviation).
