Table 1.
Nomenclature of human membrane transporters: selection transporters discussed in this paper [source: NCBI Gene (http://www.ncbi.nlm.nih.gov/gene)]
| Gene | Protein | ||
|---|---|---|---|
| Name | Locus | Name | Synonyms |
| ABC transporters | |||
| ABCB1 | 7q21.12 | ABCB1 | MDR1, P-glycoprotein (P-gp), CLCS, PGY1, ABC20, CD243, GP170 |
| ABCC2 | 10q24 | ABCC2 | MRP2, CMOAT, DJS, cMRP, ABC30 |
| ABCC3 | 17q22 | ABCC3 | MRP3, MOAT-D, cMOAT2, MLP2, ABC31, EST90757 |
| ABCC4 | 13q32 | ABCC4 | MRP4, MOAT-B, MOATB |
| ABCG2 | 4q22 | ABCG2 | BRCP, MXR, MRX, ABCP, BMDP, MXR1, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481 |
| SLC transporters | |||
| SLCO1B1 | 12p | OATP1B1 | OATP2, LST-1, OATP-C, HBLRR, LST1, SLC21A6 |
| SLCO1B3 | 12p12 | OATP1B3 | OATP8, LST-2, LST3, HBLRR, SLC21A8, LST-3TM13 |
| SLCO2B1 | 11q13 | OATP2B1 | OATP-B, SLC21A9 |
| SLC3A2 | 11q13 | 4F2hc | 4F2, CD98, MDU1, 4T2HC, NACAE, CD98HC |
| SLC22A1 | 6q25.3 | OCT1 | HOCT1, oct1_cds |
| SLC22A2 | 6q25.3 | OCT2 | |
| SLC22A6 | 11q12.3 | OAT1 | PAHT, HOAT1, ROAT1 |
| SLC22A7 | 6q21.1 | OAT2 | NLT |
| SLC22A8 | 11q11 | OAT3 | |
| SLC15A1 | 13q32.3 | PEPT1 | HPEPT1, HPECT1 |
| SLC47A1 | 17q11.2 | MATE1 | |
| SLC47A2 | 17q11.2 | MATE2-K | MATE2, MATE2-B |
| Other | |||
| FAAH | 1p35-p34 | FAAH | FAAH-1, PSAB |
| ADRB2 | 5q31-q32 | ADRB2 | BAR, B2AR, ADRBR, ADRB2R, BETA2AR |
| CDH17 | 8q22.1 | HPT1 | CDH16, LI cadherin |
ABC adenosine triphosphate (ATP)-binding cassette, ADRB2 β2-adrenergic receptor, FAAH fatty acid hydrolase, SLC solute carrier