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. 2015 Sep 26;55:507–524. doi: 10.1007/s40262-015-0328-5
Little is known about the ontogeny of transporters and their roles in pediatric pharmacotherapy.
Ex vivo, pharmacokinetic and pharmacogenetic studies suggest transporter-specific changes from the human fetus to the adult.
No clear transporter-specific maturation pattern can be deducted at this time, hence, further research is needed.