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grk Is Translationally Silenced in Nurse Cells by Being Denied Access to Its Translational Activator, Orb
A model of grk translational regulation by restricted spatial access to Orb. In the nurse cells of WT egg chambers, P bodies lack in Orb. grk mRNA does not dock with P bodies and is not translated. At the oocyte DA corner, Orb is enriched at the edge of P bodies where grk mRNA docks. grk is translated and then secreted to the follicle cells around the oocyte nucleus.
