Figure 2.

Combined pharmacological AMPK and PPARδ activation does not influence basal metabolism. Indirect calorimetry with activity measurement was conducted in the sedentary state. (A) Respiratory quotient (RQ), (B) oxygen consumption, (C) carbohydrate oxidation, (D) fat oxidation, (E) energy expenditure, and (F) spontaneous motor activity. The graph on the left depicts values at each time point while that on the right shows the average (only for RQ) or cumulative values within 24 h. Data are expressed as means ± SEM (n = 8–9). No significant differences were observed as analyzed by one‐way ANOVA.