Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 20;4(5):e12625. doi: 10.14814/phy2.12625

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Combined pharmacological AMPK and PPARδ activation promotes enhanced substrate shift during prolonged exercise in trained mice. Indirect calorimetry was conducted before and during the exercise‐to‐exhaustion test. (A) Respiratory quotient (RQ), (B) oxygen consumption, (C) carbohydrate oxidation, (D) fat oxidation, and (E) energy expenditure. The same parameters were measured during the last 30 min until exhaustion: (F) RQ, (G) oxygen consumption, (H) carbohydrate oxidation, (I) fat oxidation, and (J) energy expenditure. Time course data are expressed as means while average RQ and cumulative values are expressed as means ± SEM (n = 6). Significant differences were analyzed by one‐way ANOVA followed by Newman‐Keuls multiple comparison test. *P < 0.05; **P < 0.01; and ***P < 0.001 relative to SED.