Table 2. Multivariate Cox's Proportional Hazards Model Assessing Factors Associated With Mortality After Diagnosis of HCC.
| Risk Factor | HR* | 95% CI | P Value | |
|---|---|---|---|---|
|
| ||||
| Lower | Upper | |||
| Age, years | ||||
| <55 | Referent | |||
| 55-75 | 1.11 | 1.09 | 1.14 | <0.001 |
| >75 | 1.35 | 1.30 | 1.39 | <0.001 |
| Gender | ||||
| Female | Referent | |||
| Male | 1.07 | 1.04 | 1.09 | <0.001 |
| Race | ||||
| Other | Referent | |||
| Asian or Pacific Islander | 0.96 | 0.87 | 1.05 | 0.31 |
| White | 1.13 | 1.04 | 1.24 | 0.01 |
| Black | 1.24 | 1.13 | 1.36 | <0.001 |
| Grade | ||||
| Well differentiated | Referent | |||
| Poorly differentiated | 1.13 | 1.09 | 1.17 | <0.001 |
| Lymph/vascular invasion | ||||
| No | Referent | |||
| Yes | 1.08 | 1.05 | 1.11 | <0.001 |
| Only one primary tumor | ||||
| No | 1.12 | 1.09 | 1.16 | <0.001 |
| Yes | Referent | |||
| Tumor size, cm | ||||
| <5 | Referent | |||
| ≥5 | 1.14 | 1.11 | 1.17 | <0.001 |
| Stage | ||||
| Localized | Referent | |||
| Regional | 1.12 | 1.09 | 1.16 | <0.001 |
| Metastatic | 1.53 | 1.48 | 1.58 | <0.001 |
| Treatment modality | ||||
| Other | Referent | |||
| Resection | 0.75 | 0.69 | 0.82 | <0.001 |
| Transplant | 0.39 | 0.38 | 0.40 | <0.001 |
*
HRs greater than 1.0 indicate a higher risk of death.