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. 2016 Apr 7;6:24263. doi: 10.1038/srep24263

Table 2. Multivariate analysis for prognostic factors about T3 UT-UC recurrence.

  Local recurrence
Distant metastasis
Univariate p value Multivariate p value Univariate p value Multivariate p value
ER β  Low vs High 0.035 0.05 HR = 2.6, 95%CI = 1.0~6.9 0.004 0.008 HR = 4.8, 95%CI = 1.5~15.4
Tumor type  Infiltrating vs papillary 0.033 0.05 HR = 2.6, 95%CI = 1.0~7.9 0.092  
Nodal status  Positive vs Negative 0.468   0.013 0.998
Lymphovascular invasion  Present vs Absent 0.103   0.014 0.064
Carcinoma in situ  Present vs Absent 0.399   0.399  
SCC differentiation  Present vs Absent 0.554   0.868  
Tumor necrosis  Present vs Absent 0.975   0.975  
Tumor multifocality  Multiple vs Solitary 0.782   0.415  
Tumor grade  High vs Low 0.182   0.449  
Gender  Female vs Male 0.184   0.082  
Age  > 70 vs <=70 0.301   0.531  
Smoking  Yes vs No 0.524   0.080  
Previous bladder cancer  Yes vs No 0.189   0.008 0.997