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. 2016 Apr 7;6:24203. doi: 10.1038/srep24203

Figure 4. Effects of DNCB and TrxR1 AS-ODNs on the transnitrosylation from procaspase-9 to XIAP, and the cleavage of procaspase-9 induced by I/R.

Figure 4

(A,C) Rats were treated with DNCB, DMSO, TrxR1 AS-ODNs and TrxR1 MS-ODNs to observe their effects on the S-nitrosylation of XIAP and procaspase-9, as well as the cleavage of procaspase-9 (cleaved caspase-9). Bands were quantified, and the intensities were presented as fold-increase vs. sham. Data were the means ± S.D. from four independent experiments (n = 4). *P < 0.05 vs. the sham group, #P < 0.05 vs. the R3 group. (B) Rats were treated with TrxR1 AS-ODNs and TrxR1 MS-ODNs; TrxR1 was detected using Western blot.