Table 2.
Multidrug-resistant bacteria cultured from peritoneal fluid of patients with or without subsequent antibiotic de-escalation
| Microorganisms | De-escalation | No de-escalation | Escalation | No change |
|---|---|---|---|---|
| Total number of multidrug-resistant bacteria, n (%) | 29 (9) | 74 (24)a | 58 (28) | 16 (16)b |
| Gram-positive bacteria, n (%) | 15 (5) | 39 (13)a | 33 (16) | 6 (6)b |
| Enterococci, n (%) | 3 (1) | 9 (3) | 7 (3) | 2 (2) |
| Staphylococci, n (%) | 12 (4) | 29 (9) | 25 (12) | 4 (4) |
| Staphylococcus aureus, n (%) | – | 8 (3) | 6 (3) | 2 (2) |
| Gram-negative bacteria, n (%) | 14 (5) | 35 (11)a | 25 (12) | 10 (10) |
| Enterobacteriaceae, n (%) | 10 (3) | 24 (8) | 18 (9) | 6 (6) |
| Escherichia coli, n (%) | 1 (0) | 11 (4) | 8 (4) | 3 (3) |
| Enterobacter spp., n (%) | 5 (2) | 9 (3) | 8 (4) | 1 (1) |
| Nonfermenting Gram-negative bacilli, n (%) | 3 (1) | 11 (4) | 7 (3) | 4 (4) |
| Pseudomonas spp., n (%) | 2 (1) | 6 (2) | 4 (2) | 2 (2) |
| Total number of cultured bacteria, n | 307 | 311 | 210 | 101 |
Among the 96 patients without de-escalation, the results were analyzed in terms of subsequent antibiotic escalation or no change
a p < 0.01 versus de-escalation
b p < 0.05 versus escalation