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. 2016 Mar 24;7(3):e2157. doi: 10.1038/cddis.2015.401

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Copyright © 2016 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ARHGAP10-associated pathways in ovarian cancer. (a–c) GSEA was performed using TCGA ovarian serous cystadenocarcinoma dataset. The KEGG cell cycle, DNA replication and BER pathways were identified with the strongest association with ARHGAP10-lower expression. (d) Key moderators were determined by western blotting in A2780 and HO-8910 cells. Upper panel, representative results of western blotting; middle and lower panel, protein levels relative to GAPDH. Data were based on at least three independent experiments, and shown as mean±S.D. (*P<0.05, **P<0.01, ***P<0.001)