Table 1. Urine and serum biochemistry data of UNX C57/BL6 murine receiving 10 mg/g BSA for 4 or 8 weeks.
| BSA injection period |
1 Week |
4 Weeks |
8 Weeks |
|||
|---|---|---|---|---|---|---|
| UNX | UNX+ BSA (10 mg/g) | UNX | UNX+ BSA (10 mg/g) | UNX | UNX+ BSA (10 mg/g) | |
| UACR (μg/mg) | 270.8±88.8a | 15 677.3±5009.6a | 102.7±16.2 | 1621.8±768.4a,b | 112.9±8.7c | 6341.2±1486.6b,c |
| BUN (mg/dl) | 29.8±2.7 | 35.0±7.3c | 29.3±1.6a | 46.0±7.2a,c | 29.3±1.9a | 49.1±1.9a,c |
Abbreviations: BSA, bovine serum albumin; BUN, blood urea nitrogen; UACR, urine albumin-to-creatinine ratio; UNX, uninephrectomized
UACR and BUN were measured for the experimental animals (n=6) and expressed in mean±S.D. a=P<0.0001; b=P<0.05; c=P<0.001