Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed mechanism for Bre function in the regulation of skeletal muscle regeneration. We propose that Bre null mutation impairs skeletal muscle regeneration by reducing CXCR4 expression in satellite cells. This subsequently represses satellite cell migration to the muscle injury site. The Bre mutation also represses MyoG expression during satellite cell differentiation and fusion which further negatively impact on skeletal muscle repair.
