Table 1.

Mean erectile responses at 0 and 6 V stimulation and calculated EV₅₀ for control or with Rho-kinase inhibition in lean and obese-diabetic Zucker rats

Group	Control			100 μM H1152			N
	0 V ICP/MAP	6 V ICP/MAP	EV50 (V)	0 V ICP/MAP	6 V ICP/MAP	EV50 (V)
Lean	0.095 ± 0.009	0.860 ± 0.032	2.59 ± 0.21	0.295 ± 0.083	0.901 ± 0.049	2.13 ± 0.26	4
Obese	0.090 ± 0.003	0.572 ± 0.015*	4.25 ± 0.25*	0.177 ± 0.044	0.775 ± 0.030*‡	2.88 ± 0.43‡	4
Lean–rosuvastatin	0.107 ± 0.019	0.775 ± 0.038†	2.91 ± 0.24†	0.154 ± 0.028	0.903 ± 0.020†‡	2.51 ± 0.23	6
Obese–rosuvastatin	0.126 ± 0.010	0.818 ± 0.052†	3.95 ± 0.32*	0.283 ± 0.034‡	0.845 ± 0.016	2.74 ± 0.31‡	6

^*Different from Lean in group.

^†Different from Obese in group.

^‡Different from Control by analysis of variance with Holm–Sidak method.

EV₅₀ = voltage require to achieve 50% of the maximal response; ICP/MAP = intracavernosal blood pressure/mean arterial blood pressure.