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. Author manuscript; available in PMC: 2016 Apr 7.
Published in final edited form as: J Sex Med. 2012 Nov 21;10(3):694–703. doi: 10.1111/jsm.12001

Figure 3.

Figure 3

Effect of sepiapterin on voltage-dependent erectile response. Following the untreated voltage series (open bars), 10 µM sepiapterin was injected intracavernosally, and a voltage series was applied 30-minutes postinjection (hatched bars). No treatment effects were observed in rats fed the control diet (A), whereas rats fed the WD for 4 weeks (B), 8 weeks (C), and 12 weeks (D) demonstrated an enhanced erectile response with sepiapterin treatment. *P < 0.05, ***P < 0.001. Reported are means ± SEM for 4–6 animals in each group. ICP = intracavernosal pressure; MAP = mean arterial pressure; SEM = standard error of the mean; WD = Western diet.