Table 1.
Candidate EGFR phosphorylation sites identified in PhosphoSitePlus
| Symbol | Name | Site | Sequence |
|---|---|---|---|
| MLLT4 | Adhesion protein afadin | 1656 | RQEEGYySRLE |
| C9orf150 | Chromosome 9 open reading frame 150 | 227 | KLDSEYyCFG_ |
| CD34 | Adhesion protein CD34 | 329 | LGEDPYyTENG |
| EFNB1 | Membrane protein of the Ephrin family | 343 | SPANIYyKV__ |
| EIF2A | Eukaryotic translation initiation factor 2A | 250 | KTGASYyGEQT |
| EMD | Nuclear membrane protein emerin | 94 | GYNDDYyEESY |
| PTK2 | Focal adhesion kinase FAK | 576 | MEDSTYyKASK |
| ERBB2 | Receptor tyrosine kinase HER2 | 1221 | AFDNLYyWDQD |
| JAK1 | Janus kinase 1 | 1034 | ETDKEYyTVKD |
| LSR | Lipolysis stimulated lipoprotein LISCH | 406 | SMRVLYyMEKE |
| MET | HGF receptor tyrosine kinase | 1234 | MYDKEYySVHN |
| ERRFI1 | EGFR Negative regulator MIG-6 | 394 | VSSTHYyLLPE |
| PKP4 | Adhesion protein plakophilin 4 | 420 | YEGRTYySPVY |
| PVRL3 | Nectin family adhesion protein PVRL3 | 510 | ERPMDYyEDLK |
| SHC1 | Adaptor protein Shc1 | 239 | PPDHQYyNDFP |
| INPPL1 | Inositol phosphatase SHIP-2 | 986 | FNNPAYyVLEG |
| SKT | Skeletal development protein SKT | 244 | ESRNVYyELND |
| TANC2 | Ankyrin-repeat containing protein TANC2 | 1919 | LLEDDYySPHG |
The PhosphoSitePlus database was searched for sites that conform to the EGFR YpY motif and whose phosphorylation correlates with EGFR activity. Putative phosphorylation sites are shown in bold. Phosphorylated tyrosines are shown in lower case.